Selected recent publications: Granger R (2005) Engines of the Brain: The computational instruction set of human cognition. AI Journal (In press). pdf Rodriguez, A., Whitson, J., Granger, R. (2004). Derivation and analysis of basic computational operations of thalamocortical circuits. Journal of Cognitive Neuroscience, 16: 856-877. pdf Granger R. (2004) Brain circuit implementation: High-precision computation from low-precision components. In: Toward Replacement Parts for the Brain (T.Berger, D.Glanzman, Eds.) Mass: MIT Press., pp.277-294. pdf Granger, R. (2003). Neural Computation: Olfactory cortex as a model for telencephalic processing. Learning & Memory (J.Byrne, Ed.), pp.445-450. pdf Benvenuto, J., Jin, Y., Casale, M., Lynch, G., Granger, R. (2002). Identification of diagnostic evoked response potential segments in Alzheimer¹s Disease. Exper. Neurology, 176: 269-276. pdf Phillips, D, Sonnenberg, J, Arai, A, Vaswani, R, Krutzik, P, Kleisli, T, Kessler, M, Granger, R, Lynch, G, Chamberlin, R (2002). 5'-Alkyl-benzothiadiazides: A new subgroup of AMPA receptor modulators with improved affinity. Bioorganic & Medicinal Chem. 10: 1229-1248. pdf Arai, A, Yan-Fang, X, Kessler, M, Phillips, D, Chamberlin, R, Granger, R, Lynch, G. (2002). Effects of 5'-Alklyl-Benzothiadiazides on AMPA receptor biophysics and synaptic responses. Molecular Pharmacology, 62: 566-577. pdf Shimono, K., Taketani, M., Brucher, F., Kubota, D., Colgin, L., Robertson, S., Granger R., Lynch, G. (2001). Continuous two-dimensional current-source density analyses of electrophysiological activity in hippocampal slices. Neurocomputing 38: 899-905. pdf Granger, R. (2001). Method and computer program product for assessing neurological conditions and treatments using evoked response potentials. U.S. Patent # 6,223,074 (54 claims). Granger, R., and Lynch, G. (2001). Method and apparatus for assessing susceptibility to stroke. U.S. Patent # 6,280,393 (17 claims). Granger, R. (2001). NeuroGraph Evoked Potential System. Food and Drug Administration (FDA) 510(k) clearance #K010669. Shimono, K., Brucher, F., Granger, R., Lynch, G., and Taketani, M. (2000). Origins and distribution of cholinergically induced beta rhythms in hippocampal slices. J. Neuroscience 20: 8462-8473. pdf Lynch, G., Granger, R., Gall, C., Palmer, L. (2000). Assay for determination of neuronal activity in brain tissue. U.S. Patent # 5,998,139 (6 claims). Lynch, G., and Granger, R. (2000). Method for treating sexual dysfunctions. U.S. Patent # 6,083,947 (33 claims). Davis, M. Ambros-Ingerson, J., Granger, R., Wu, J., Zabaneh, R., Abdelnaby, M, and Lynch, G. (1998). Triazolam impairs delayed recall but not acquisition of various everyday memory tasks in humans. Experimental Neurol., 148: 124-134. pdf Kilborn, K., Kubota, D., Lynch, G, and Granger, R. (1998). Parameters of LTP induction modulate network categorization behavior. In: Computational Neurosci (NY: Plenum), 353-358. Davis, M., Moskovitz, B., Nguyen, M., Lynch, G., Rogers, G., Granger, R. (1997). A profile of the behavioral changes produced by facilitation of AMPA-type glutamate receptors. Psychopharmacology, 133: 161-167. Garzotto, A., Aleksandrovsky, B., Lynch, G., Granger, R. (1997). A neocortically derived model of continuous contextual processing. IEEE Press, Proc. Int¹l Conf Neural Networks, 1: 564-568. 16. Aleksandrovsky, B., Brucher, F., Lynch, G., Granger, R. (1997). Neural network model of striatal complex. In: Biological and Artificial Computation: From Neuroscience to Technology. Int¹l Conf on Artificial and Natural Neural Networks, Berlin: Springer-Verlag, pp.104-115. Hess, U.S., Granger, R., Lynch, G., Gall, C.M. (1997). Differential patterns of c-fos mRNA expression in amygdala during successive stages of odor discrimination learning. Learning and Memory, 4: 262-283. Lynch, G., Granger, R., Davis, M., Ambros-Ingerson, J., Kessler, M., Schehr, R. (1997). Evidence that a positive modulator of glutamate receptors improves recall in elderly human subjects. Experimental Neurol., 145: 89-92. Ingvar, M., Ambros-Ingerson, J., Davis, M., Granger, R., Kessler, M., Rogers, G, Schehr, R., and Lynch., G. (1997). Enhancement by an ampakine of memory encoding in humans. Exper. Neurol., 146: 553-559. pdf Granger, R., Wiebe, S., Taketani, M., Ambros-Ingerson, J., Lynch, G. (1996). Distinct memory circuits comprising the hippocampal region. Hippocampus, 6: 567-578. pdf Kilborn, K., Lynch, G., and Granger, R. (1996). Effects of LTP on response selectivity of simulated cortical neurons. J. Cog. Neurosci., 8: 328-343. pdf Aleksandrovsky, B., Whitson, J., Andes, G., Lynch, G., Granger, R. (1996). Novel speech processing mechanism derived from auditory neocortical circuit analysis. IEEE Press, Proc. ICSLP Int¹l Conf. on Spoken Language, 1: 558-561. Lynch, G., Kessler, M., Rogers, G., Ambros-Ingerson, J., Granger, R. and Schehr, R. (1996). Psychological effects of a drug that facilitates brain AMPA receptors. Int J Clinical Psychopharmacol, 11: 13-19. Granger, R., Deadwyler, S., Davis, M., Moskowitz, B., Kessler, M., Rogers, G., and Lynch, G. (1996). Facilitation of glutamate receptors reverses an age-associated memory impairment in rats. Synapse, 22: 332-337. Aleksandrovsky, B., Whitson, J., Garzotto, A, Lynch, G., Granger, R. (1996). An algorithm derived from thalamocortical circuitry stores and retrieves temporal sequences. IEEE Comp.Soc.Press, Proc. Int¹l Conf. Pattern Recog., 4: 550-554. Myers, C., Gluck, M., and Granger, R. (1995). Dissociation of hippocampal and entorhinal function in associative learning: A computational approach. Psychobiology, 23: 116-138. Ozeki, T., Shouval, H., Intrator, N. and Granger, R. (1995). Analysis of a temporal sequence learning network based on the property of LTP induction. In: Int'l Symposium on Nonlinear Theory, Las Vegas. Granger, R. and Lynch, G. (1994). Cognitive modularity: Computational division of labor in the brain. In: The Handbook of Neuropsychology, New York: Academic Press. 9: 263-277. Kowtha, V., Satyanarayana, P., Granger, R., and Stenger, D. (1994). Learning and classification in a noisy environment by a simulated cortical network. Proc. Third Ann. Comp. & Neural Systems Conf., Boston: Kluwer, pp. 245-250. Coultrip, R. and Granger, R. (1994). LTP learning rules in sparse networks approximate Bayes classifiers via Parzen's method. Neural Networks, 7: 463-476. Granger, R., Whitson, J., Larson, J. and Lynch, G. (1994). Non-Hebbian properties of LTP enable high-capacity encoding of temporal sequences. Proc. Nat'l. Acad. Sci., 91: 10104-10108. Gluck, M. and Granger, R. (1993). Computational models of the neural bases of learning and memory. Ann. Rev. Neurosci. 16: 667-706. Granger, R., Staubli, U., Davis, M., Perez, Y., Nilsson, L., Rogers, G., and Lynch, G. (1993). A drug that facilitates glutamatergic transmission reduces exploratory activity and improves performance in a learning-dependent task. Synapse, 15: 326-329. Anton, P., Granger, R., and Lynch, G. (1993). Simulated dendritic spines influence reciprocal synaptic strengths and lateral inhibition in the olfactory bulb. Brain Res., 628: 157-165. Anton, P., Granger, R. and Lynch, G. (1992). Temporal information processing in synapses, cells and circuits. In: Single neuron computation, (McKenna, Davis and Zornetzer, Eds.), NY: Academic Press, 291-313. Coultrip, R., Granger, R., and Lynch, G. (1992). A cortical model of winner-take-all competition via lateral inhibition. Neural Networks, 5: 47-54. Lynch, G. and Granger, R. (1992). Variations in synaptic plasticity and types of memory in cortico-hippocampal networks. J. Cog. Neurosci., 4: 189-199. Anton, P., Lynch, G., and Granger, R. (1991). Computation of frequency-to-spatial transform by olfactory bulb glomeruli. Biol. Cybern., 65: 407-414. Granger, R., and Lynch, G. (1991). Higher olfactory processes: Perceptual learning and memory. Current Opin. Neurosci., 1: 209-214. Granger, R., Staubli, U., Powers, H., Otto, T., Ambros-Ingerson, J., and Lynch, G. (1991). Behavioral tests of a prediction from a cortical network simulation. Psychol. Sci., 2: 116-118. McCollum, J., Larson, J., Otto, T., Schottler, F. Granger, R., and Lynch, G. (1991). Short-latency single-unit processing in olfactory cortex. J. Cog. Neurosci., 3: 293-299. Lynch, G., Larson, J., Staubli, U., Ambros, J., and Granger, R. (1991). Long-term potentiation and memory operations in cortical networks. In Perspectives on Cognitive Neuroscience, Lister, R., and Weingartner, H. (Eds.), New York: Oxford Univ. Press, 110-131. Granger, R., Staubli, U., Ambros-Ingerson, J., and Lynch, G. (1991). Specific behavioral predictions from simulations of the olfactory system. In: Olfaction as a model system for computational neuroscience, (H.Eichenbaum and J.Davis, Eds.), Cambridge: MIT Press. Lynch, G., Granger, R., and Larson, J. (1990). Empirically derived synaptic learning rules and the phenomenology of memory. FESN Discussions in Neuroscience, 6: 85-89. Lynch, G. and Granger, R. (1990). Olfactory rhythms and the encoding of memory. Proc. 10th Internat. Symp. on Olfaction and Taste, Oslo, Norway, 246-264. Ambros-Ingerson, J., Granger, R., and Lynch, G. (1990). Simulation of paleocortex performs hierarchical clustering. Science, 247: 1344-1348.