MUpro: Prediction of Protein Stability Changes for Single-Site Mutations from Sequences (Help)

Mutation Name(optional):
Mutation Position:

Original Amino Acid:

Substitute Amino Acid:

Protein sequence(one plain sequence, no headers):

Specify the protein structure file if available (optional):

See example



Download MUpro Source Code, Software and Datasets


Reference:
[1] J. Cheng, A. Randall, and P. Baldi. Prediction of Protein Stability Changes for Single-Site Mutations Using Support Vector Machines. Proteins: Structure, Function, Bioinformatics, vol. 62, no. 4, pp. 1125-1132, 2006. [PDF]

[2] J. Cheng, A. Z. Randall, M. Sweredoski, and P. Baldi. SCRATCH: a Protein Structure and Structural Feature Prediction Server. Nucleic Acids Research, vol. 33 (server issue), w72-76, 2005. [PDF]

Institute for Genomics and Bioinformatics
School of Information & Computer Science
University of California Irvine
Mupro Server Statistics
Contact: Paul Rigor at prigor@ics.uci.edu, Pierre Baldi at pfbaldi@ics.uci.edu or Jianlin Cheng at jianlinc@uci.edu